Publications

2020

Quan L, Lin Z, Lin Y, Wei Y, Lei L, Li Y, Tan G, Xiao M, Wu T*. Glucose-modification of cisplatin to facilitate cellular uptake, mitigate toxicity to normal cells, and improve anti-cancer effect in cancer cells. Journal of Molecular Structure 2020, 1203: 127361

2019


Qiu J, Yuan Y, Li Y, Haley C, Mui UN, Swali R, Mohan C, Tyring SK, Wu T*. Discovery of IgG4 Anti-Gliadin Autoantibody as a Potential Biomarker of Psoriasis Using an Autoantigen Array. Proteomics Clin Appl. 2019 Oct 31:e1800114. doi: 10.1002/prca.201800114. [Epub ahead of print] PMID: 31671471 *Corresponding author.

Quan L*, Gu J, Lin W, Wei Y, Lin Y, Liu L, Ding H, Pan C, Xie Z*, Wu T*. A BODIPY biosensor to detect and drive self-assembly of diphenylalanine. Chem Commun (Camb). 2019 Jul 4. doi: 10.1039/c9cc03810h. [Epub ahead of print] PMID: 31271158. *Corresponding author.

Ye Y, Wu T, Zhang T, Han J, Habazi D, Saxena R, Mohan C. Elevated oxidized lipids, anti-lipid autoantibodies and oxidized lipid immune complexes in active SLE. Clin Immunol. 2019 May 7;205:43-48. doi: 10.1016/j.clim.2019.05.004. [Epub ahead of print] PMID: 31075396.

Yuan Y, Qiu J, Lin ZT, Li W, Haley C, Mui UN, Ning J, Tyring SK, Wu T*. Identification of Novel Autoantibodies Associated with Psoriatic Arthritis. Arthritis Rheumatol. 2019 Jan 7. doi: 10.1002/art.40830. [Epub ahead of print] PMID: 30618213.  *corresponding author.

2018


Ding H, Wu T*. Insulin-Like Growth Factor Binding Proteins in Autoimmune Diseases. 2018. Front. Endocrinol., 30 August 2018 | https://doi.org/10.3389/fendo.2018.00499*corresponding author.

Li C, Yu J, Xu S, Jiang S, Xiu X, Chen C, Liu A, Wu T, Man B, Zhang C. Constructing 3D and Flexible Plasmonic Structure for High-Performance SERS Application. 2018. Adv. Mater. Technol. 2018 Aug, DOI: 10.1002/admt.201800174.

Guo Y, Yu J, Li C, Li Z, Pan J, Liu A, Man B, Wu T, Xiu X, Zhang C. SERS substrate based on the flexible hybrid of polydimethylsiloxane and silver colloid decorated with silver nanoparticles. 2018. OPTICS EXPRESS  26 (17) 21784

Li M, Li X, Liu Y, Liu X, Song Y, Zhao J, Mohan C, Wu T, Peng A, Qin L. Relationship between serum bilirubin levels and the progression of renal function in patients with chronic kidney disease and hyperuricemia. Clin Chim Acta. 2018 Aug 1;486:156-161. doi: 10.1016/j.cca.2018.07.045. [Epub ahead of print]

Qiu J, Keyser B, Lin ZT, Wu T*. Autoantibodies as Potential Biomarkers in Breast Cancer. Biosensors. 2018, 8, 67. *corresponding author.

Hong X, Jiang S, Marmolejo N, Vangipuram R, Ramos-Rojas E, Yuan Y, Lin ZT, Li Y, Qiu J, Xing Y, Haley C, Tyring SK, Wu T*. Serum VEGFR-3 as a potential biomarker in psoriasis. Exp Dermatol  2018 Jun 29. doi: 10.1111/exd.13727. [Epub ahead of print]   *Corresponding author

Lin ZT, Li Y, Gu J, Wang H, Zhu Z, Hong X, Zhang Z, Lu Q, Qiu J, Wang X, Bao J, Wu T*  A Conductive Nanowire‐Mesh Biosensor for Ultrasensitive Detection of Serum C‐Reactive Protein in Melanoma. Advanced Functional Materials.  2018 June 5, DOI: 1002/adfm.201802482 . *Corresponding author

Li Y, Wu T*. Proteomic approaches for novel systemic lupus erythematosus (SLE) drug discovery. Expert Opin Drug Discov. 2018 Jun 4:1-13. doi: 10.1080/17460441.2018.1480718. [Epub ahead of print] PMID: 29863906    *Corresponding author.

Lin ZT, DeMarr V, Bao J, Wu T*   Molecularly Imprinted Polymer-Based Biosensors: For the Early, Rapid Detection of Pathogens, Biomarkers, and Toxins in Clinical, Environmental, or Food Samples. IEEE Nanotechnology Magazine 2018, 12 (1), 6-13   *Corresponding author.

 

2017


Yuan Y, Lin ZT, Wang H, Hong X, Heon M, Wu T*: Protein Arrays I: Antibody Arrays. Methods Mol Biol  2017, 1654:261-269. PMID: 28986797. *Corresponding author.

Yuan Y, Wang H, Lin ZT, Hong X, Heon M, Wu T*: Protein Arrays II: Antigen Arrays. Methods Mol Biol  2017, 1654:271-277. PMID: 28986798. *Corresponding author.

Yuan Y, Hong X, Lin ZT, Wang H, Heon M, Wu T*: Protein Arrays III: Reverse-Phase Protein Arrays. Methods Mol Biol  2017, 1654:279-289. PMID: 28986799. *Corresponding author.

Selvam AP, Wangzhou A, Jacobs M, Wu T, Mohan C, Prasad S. Development and validation of an impedance biosensor for point-of-care detection of vascular cell adhesion molecule-1 toward lupus diagnostics. Future Sci. OA 2017  FSO224 eISSN 2056-5623.

Lin ZT, Gu J, Li CH, Lee TR, Xie L, Chen S, Cao PY, Jiang S, Yuan Y, Hong X, Wang H, Wang D, Wang X, Jiang GB, Heon M, Wu T*. A Nanoparticle-Decorated Biomolecule-Responsive Polymer Enables Robust Signaling Cascade for Biosensing. Adv Mater. 2017 Jun 14. doi: 10.1002/adma.201702090. [Epub ahead of print] PMID: 28612952.  *Corresponding author.

 

2016


Zhang X, Zambrano A, Lin ZT, Xing Y, Rippy J, Wu T*. Immunosensors for Biomarker Detection in Autoimmune Diseases. Arch Immunol Ther Exp (Warsz). 2016 Sep 3. [Epub ahead of print] Review. PMID: 27592176.  *Corresponding author

Wang H, Lin ZT, Yuan Y, Wu T*. Urine biomarkers in renal allograft. J Transl Int Med. 2016 Sep 1;4(3):109-113. doi: 10.1515/jtim-2016-0032. Epub 2016 Sep 23. PMID: 28191531.  *Corresponding author.

Orme JJ, Du Y, Vanarsa K, Wu T, Satterthwaite AB, Mohan C. Leukocyte Beta-Catenin Expression Is Disturbed in Systemic Lupus Erythematosus. PLoS One.  2016 Aug 22;11(8):e0161682. doi:  10.1371/journal.pone.0161682. eCollection 2016. PMID: 27548498

Huang JF*, Zhong J*, Chen GP*, Lin ZT*, Deng Y, Liu YL, Cao PY, Wang B, Wei Y, Wu T, Yuan J, Jiang GB. A Hydrogel-Based Hybrid Theranostic Contact Lens for Fungal Keratitis. ACS Nano. 2016 May 31. [Epub ahead of print]  PMID: 27244244  * Co-first authors.

Orme JJ, Du Y, Vanarsa K, Mayeux J, Li L, Mutwally A, Arriens C, Min S, Hutcheson J, Davis LS, Chong BF, Satterthwaite AB, Wu T, Mohan C. Heightened Cleavage of Axl Receptor Tyrosine Kinase by ADAM metalloproteases may contribute to disease pathogenesis in SLE. Clin Immunol. 2016 May 26. pii: S1521-6616(16)30084-5. doi: 10.1016/j.clim.2016.05.011. [Epub ahead of print]   PMID: 27237127

Wu T *, Ding H, Han J, Arriens C, Wei C, Han W, Pedroza C, Jiang S, Anolik J, Petri M, Sanz I, Saxena R, Mohan C*. Antibody array based proteomic screening of serum markers in systemic lupus erythematosus – a discovery study. J Proteome Res. 2016 May 23. [Epub ahead of print] PMID: 27211902     *Corresponding authors.

Du Y, Wu T, Zhou XJ, Davis LS, Mohan C. Blockade of CD354 (TREM-1) Ameliorates Anti-GBM-Induced Nephritis. Inflammation. 2016 Apr 15. [Epub ahead of print] PMID: 27083877

Wu T, Xie C, Han J, Ye Y, Singh S, Zhou J, Li Y, Ding H, Li QZ, Zhou X, Putterman C, Saxena R, Mohan C. Insulin-Like Growth Factor Binding Protein-4 as a Marker of Chronic Lupus Nephritis. PLoS One. 2016 Mar 28; 11(3):e0151491. doi: 10.1371/journal.pone.0151491. PMID: 27019456

Zhou R, Kang X, Tang B, Mohan C, Wu T, Peng A, Liu JY. Ornithine is a key mediator in hyperphosphatemia-mediated human umbilical vein endothelial cell apoptosis: Insights gained from metabolomics. Life Sci. 2016 Feb 1; 146:73-80. doi: 10.1016/j.lfs.2016.01.003. Epub 2016 Jan 8. PMID: 26773858

Ding H, Kharboutli M, Saxena R, Wu T*. IGFBP-2 as a novel biomarker for disease activity and renal pathology changes in lupus nephritis. Clin Exp Immunol. 2016 Apr;184(1):11-8. doi: 10.1111/cei.12743. Epub 2016 Jan 11. PMID: 26616478. *Corresponding author.

Hinchliffe TE, Lin ZT, Wu T*. Protein arrays for biomarker discovery in lupus. Proteomics Clin Appl. 2016 Jan 22. doi: 10.1002/prca.201500060. [Epub ahead of print] Review. PMID: 26684273. *Corresponding author.

 

2015


Jiang S, Hinchliffe TE, Wu T*. Biomarkers of An Autoimmune Skin Disease – Psoriasis. Genomics Proteomics Bioinformatics. 2015 Aug;13(4):224-33. doi: 10.1016/j.gpb.2015.04.002. Epub 2015 Sep 8. Review. PMID: 26362816. *Corresponding author.

Lin ZT, Wu T*. Theranostic Nanoparticles for Rheumatoid Arthritis. Rev. Nanosci. Nanotechnol. 2015. 4, 67-79. *Corresponding author.

Xu W, Wang L, Wang Q, Li XH, Hu D, Li C, Wu T, Mohan C, Peng A, Shi Y. Paraquat Poisoning Followed by Toxic Epidermal Necrolysis: A Report of Two Cases and Published Work Review. Dermatology. 2015 Jul 24. [Epub ahead of print] PMID: 26228174

Zhou CY, Kang X, Li CB, Li XH, Liu Y, Wang Z, Wang L, Wu T, Mohan C, Hu DY, Peng A.Pneumomediastinum predicts early mortality in acute paraquat poisoning. Clin Toxicol (Phila). 2015 Jul;53(6):551-6. doi: 10.3109/15563650.2015.1046183. Epub 2015 Jun 13. PMID: 26072933

Qin L, Tang B, Deng B, Mohan C, Wu T, Peng A. Extracellular regulated protein kinases play a key role via bone morphogenetic protein 4 in high phosphate-induced endothelial cell apoptosis. Life Sci. 2015 Jun 15; 131:37-43. doi: 10.1016/j.lfs.2015.03.017. Epub 2015 Apr 18. PMID: 25896660

Kang X, Hu DY, Li CB, Li XH, Fan SL, Liu Y, Tang GY, Ai ZS, Wu T, Mohan C, Zhou XJ, Liu JY, Peng A.The volume ratio of ground glass opacity in early lung CT predicts mortality in acute paraquat poisoning. PLoS One. 2015 Apr 1;10(4):e0121691. doi: 10.1371/journal.pone.0121691. eCollection 2015.PMID: 25830638

Hutcheson J, Ye Y, Han J, Arriens C, Saxena R, Li QZ, Mohan C, Wu T*. Resistin as a potential marker of renal disease in lupus nephritis. Clin Exp Immunol. 2015 Mar;179(3):435-43. doi: 10.1111/cei.12473. PMID: 25345756 *Corresponding author.

Wang L, Wu J, Cheng JF, Liu XY, Ma F, Guo LH, Xu JM, Wu T, Mohan C, Peng A, Xu HX, Song YX. Diagnostic value of quantitative contrast-enhanced ultrasound (CEUS) for early detection of renal hyperperfusion in diabetic kidney disease. J Nephrol. 2015 Feb 25. [Epub ahead of print] PMID: 25712236

 

2014


Zheng D, Li C, Wang S, Cang Y, Song Y, Liu X, Li X, Mohan C, Wu T, Hu D, Peng A. Life Sci. 2015 Jan 12. pii: S0024-3205(15)00006-5. doi: 10.1016/j.lfs.2014.12.023. [Epub ahead of print]  PMID: 25592138

Wang L, Cheng J, Sun LP, Song YX, Guo LH, Xu JM, Wu T, Mohan C, Peng A, Xu H, Liu XY. Use of Contrast-Enhanced Ultrasound to Study Relationship between Serum Uric Acid and Renal Microvascular Perfusion in Diabetic Kidney Disease. BioMed Research International 2014. ID 732317.

Wang S, Qin L, Wu T, Deng B, Sun Y, Hu D, Mohan C, Zhou XJ, Peng A. Elevated cardiac markers in chronic kidney disease as a consequence of hyperphosphatemia-induced cardiac myocyte injury. Med Sci Monit. 2014 Oct 25;20:2043-53

Wu T, Ye Y, Min S, Zhu J,  Khobahy E, Zhou J, Yan M, Hemachandran S, Pathak S, Zhou X, Andreef M and Mohan C. Prevention of murine lupus nephritis by targeting multiple signaling axes and oxidative stress using a synthetic triterpenoid. Arthritis Rheumatol. 2014 Nov;66(11):3129-39. doi: 10.1002/art.38782. PMID: 25047252

 

2013


Becker AM, Dao KH, Han BK, Kornu R, Lakhanpal S, Mobley AB, Li QZ, Lian Y, Wu T, Reimold AM, Olsen NJ, Karp DR, Chowdhury FZ, Farrar JD, Satterthwaite AB, Mohan C, Lipsky PE, Wakeland EK, Davis LS.SLE Peripheral Blood B Cell, T Cell and Myeloid Cell Transcriptomes Display Unique Profiles and Each Subset Contributes to the Interferon Signature. PLoS One. 2013 Jun 24;8(6):e67003.

Wu T*, Du Y, Han J, Singh S, Xie C, Guo Y, Zhou XJ, Ahn C, Saxena R, and Mohan C*. Urinary Angiostatin – a novel marker of renal pathology chronicity in lupus nephritis. 2012. Molecular and cellular Proteomics 2013 Jan 23. May; 12(5):1170-9. [Epub ahead of print] PMID: 23345539. *Corresponding author.

Min S, Yan M, Du Y, Wu T, Khobahy E, Kwon S, Taneja S, Bashmakov A, Mohan C. Intra-articular Nf-kB Blockade Ameliorates Collagen‐induced Arthritis in Mice by Eliciting Regulatory T Cells and Macrophages. Clinical & Experimental Immunology. Pub ahead of print: Jan 2013, DOI: 10.1111/cei.12054.

 

2012


Vanarsa K, Ye Y, Han J, Xie C, Mohan C*, Wu T*. Inflammation associated anemia andferritin as disease markers in systemic lupus erythematosus. Arthritis Res Ther. 2012 Aug 7;14(4):R182. [Epub ahead of print] PMID:22871034. * Corresponding author.

Wu T, Mohan C. Lupus nephritis – alarmins may sound the alarm? Arthritis Res Ther. 2012 Dec 31;14(6):129.

Singh S*, Wu T*, Xie C, Vanarsa K, Han J, Mahajan T, Oei HB, Ahn C, Zhou XJ, Putterman C, Saxena R, Mohan C. Urine VCAM-1 as a marker of renal pathology activity index in lupus nephritis. Arthritis Res Ther. 2012 Jul 13;14(4):R164. [Epub ahead of print] PMID:22788914 *Joint first authors.

Yang Y, Ye Y, Liang L, Wu T, Zhan Z, Yang X, Xu H.Systemic-lupus-erythematosus-related acute pancreatitis: a cohort from South china. Clin Dev Immunol. 2012;2012:568564. Epub 2012 Jun 19. PMID:22761631

Wu T, Xie C, Han J, Ye Y, Weiel J, Li Q, Blanco I, Ahn C, Olsen N, Putterman C, Saxena R.Mohan C. (2012) Metabolic Disturbances Associated with Systemic Lupus Erythematosus. PLoS ONE 7(6): e37210. PMCID: PMC3378560.

Min SY, Fu Y, Hutcheson J, Wu T, Khobahy E, Zhu J, Vanarsa K, Du Y, Park MJ, Park HS, Saxena R, Kim HY, Mohan C.Peritoneal catheter implantation elicits IL-10-producing immune-suppressor macrophages through a MyD88-dependent pathway. Clin Immunol. 2012 Apr;143(1):59-72.

Kiani A*, Wu T*, Fang H, Zhou XJ, Ahn C, Magder LS, Mohan C, Petri M. (2012) Urinary Vascular Cell Adhesion Molecule (VCAM-1) but not Neutrophil Gelatinase-Associated Lipocalin (NGAL) is Associated with Lupus Nephritis. J Rheumatol. 2012 Jun;39(6):1231-7. Epub 2012 Apr 15. PMID: 22505707.* Joint first authors.

Ma F, Cang Y, Zhao B, Liu Y, Wang C, Liu B, Wu T, Peng A. (2012) Contrast-Enhanced Ultrasound with SonoVue could accurately assess the renal microvascular perfusion in diabetic kidney damage. Nephrol Dial Transplant. 2012 Jul;27(7):2891-8. Epub 2012 Apr 24. PMID:22532616

 

2011


Peng, A*, Wu, T*, Zeng, C, Rakheja, D, Zhu, J, Ye, T., Hutcheson, J, Vaziri, ND, Liu, Z, Mohan, C, Zhou, XJ. (2011) Adverse Effects of Simulated Hyper- and Hypo-Phosphatemia on Endothelial Cell Function and Viability. PLoS One. 2011; 6(8): e23268. * Joint first authors. PMCID: PMC3153490

Lu H*, Zhen J*, Wu T*, Peng A, Ye T, Wang T, Yu X, Vaziri ND, Mohan C, Zhou XJ. (2010) Superoxide dismutase mimetic drug tempol aggravates anti-GBM antibody induced glomerulonephritis in mice. Am J Physiol Renal Physiol. 299 (2):445-452. *Joint first authors.

 

2010


Wu, T., Sajitharan, D., Mohan, C. Biomarkers of rheumatoid arthritis: recent progress. Expert Opinion on Medical Diagnostics. 2010. 4(4): 293-305.

Wu T, Fu Y, Brekken D, Yan M, Zhou XJ, Vanarsa K, Deljavan N, Ahn C, Putterman C, Mohan C. (2010) Urine proteome scans uncover total urinary protease, Prostaglandin D synthase, Serum amyloid P, and Superoxide dismutase as potential markers of lupus nephritis. J Immunol. 2010, 184(4):2183-93. PMCID: PMC2927858

 

2009


Santiago-Raber ML, Dunand-Sauthier I, Wu T, Li QZ, Uematsu S, Akira S, Reith W, Mohan C, Kotzin BL, Izui S. (2009) Critical role of TLR7 in the acceleration of systemic lupus erythematosus in TLR9-deficient mice. J Autoimmun. 2009 Nov 25. [Epub ahead of print]

Wu, T., Mohan, C. (2009) The AKT axis as a therapeutic target in autoimmune diseases.. Endocrine, Metabolic & Immune Disorders – Drug Targets, 9(2):145-50.

Wu, T., Mohan, C. Proteomics as a tool for biomarker discovery in autoimmune diseases. 2009. Autoimmun Rev. 8(7):595-8. PMID: 19393208.

 

2008


Hutcheson J, Scatizzi JC, Siddiqui AM, Haines GK 3rd, Wu T, Li QZ, Davis LS, Mohan C, Perlman H. (2008) Combined Deficiency of Proapoptotic Regulators Bim and Fas Results in the Early Onset of Systemic Autoimmunity. 2008. Immunity 28, 206–217. PMID: 18275831

 

2007


Wu T, Xie C, Wang HW, Zhou XJ, Schwartz N, Calixto S, Mackay M, Aranow C, Putterman C, Mohan C. (2007). Elevated urinary VCAM-1, P-selectin, sTNFR-1 and CXCL16 in multiple lupus strains and human lupus nephritis. The Journal of Immunology, 179(10):7166-75. PMID: 17982109

Wu T, Qin X, Kurepa Z, Kumar KR, Liu K, Kanta H, Zhou XJ, Satterthwaite AB, Davis LS, Mohan C. (2007). Shared signaling networks active in B cells isolated from genetically distinct mouse models of lupus. J Clin Invest., 117(8): 2186–2196. PMCID: PMC1913486

Xie C, Patel R, Wu T*, Zhu J, Henry T, Bhaskarabhatla M, Samudrala R, Tus K, Gong Y, Zhou H, Wakeland EK, Zhou XJ, Mohan C. (2007). PI3K/AKT/mTOR hypersignaling in autoimmune lymphoproliferative disease engendered by the epistatic interplay of Sle1b and FASlpr. Int Immunol. 19(4):509-22. (*Joint First Authorship)

Wu T, Xie C, Bhaskarabhatla M, Yan M, Leone A, Chen SS, Zhou XJ, Putterman C, Mohan C. (2007). Excreted urinary mediators in immune nephritis with potential pathogenic significance. Arthritis & Rheumatism, 56(3): 949-959. PMID: 17328072

Wu T, Mohan C. 2007. Three pathogenic determinants in immune nephritis − anti-glomerular antibody specificity, innate triggers and host genetics. Frontiers in Biosciences, 12, 2207-2211. PMID: 17127457

Wu T and Mohan C. 2007. Proteomics on the diagnostic horizon-Lessons from Rheumatology. Am. J. Med. Sci. 333 (1): 16-25. PMID: 17220690

 

Before 2007


Mehrad B, Park SJ, Akangire G, Standiford TJ, Wu T, Zhu J, Mohan C. The lupussusceptibility locus, Sle3, mediates enhanced resistance to bacterial infections. J Immunol. 2006 Mar 1;176(5):3233-9. PMID:16493084

Li QZ, Xie C, Wu T, Mackay M, Aranow C, Putterman C, Mohan C. Identification of autoantibody clusters that best predict lupus disease activity using glomerular proteome arrays. J Clin Invest. 2005 Dec;115(12):3428-39. PMCID: PMC1297234

Vakonakis I, Sun J, Wu T, Holzenburg A, Golden SS, LiWang AC. NMR structure of the KaiC-interacting C-terminal domain of KaiA, a circadian clock protein: mplications for  KaiAKaiC interaction. Proc Natl Acad Sci U S A. 2004 Feb 10;101(6):1479-84. PMID: 14749515.

Wu T, Song L, Liu Y. Construction and analysis of a high-CO2-requiring mutant of the cyanobacterium Anabaena sp. strain PCC7120. Aust J Plant Physiol. 2000.  27(11) 1077 – 1083

Wu T, Song L, Liu Y. Selection and Ultrastructural Observation of a High-CO2-requiring Mutant of Cyanobacterium Synechococcus sp. PCC7942 . J. Integrative Plant Biology 2000 42(2): 116-121.

Wu T, Song L, Liu Y. Characterization of carboxysomal carbonic anhydrase in cyanobacterium Anabaena sp. PCC7120. Acta Hydrobiologica Sinica. 1999. 25 (5): 409-413

Wu T, Song L, Liu Y.  An inducible CO2 concentrating mechanism in cyanobacterium Anabaena sp. strain PCC7120. 1999. Science Bulletin 44(23):2177-2181.

Wu T, Song L, Liu Y.  Physiological aspects of a high-CO2 requiring mutant and the high-CO2 growing cells of the cyanobacterium Synechococcus sp. PCC7942. Chinese Journal of Oceanology and Limnology. 1998; 16:133-139.